Research Fellow - The Tiwari Lab

Queen's University Belfast

Research Fellow – The Tiwari Lab

School of Medicine, Dentistry & Biomedical Sciences (MDBS)

Ref: 22/110067

Duration: Fixed Term – 12 months

Hours: Full-time

Salary: £34,304 – £40,927 per annum

The School of Medicine, Dentistry & Biomedical Sciences (MDBS) at Queen’s University Belfast, is currently seeking to appoint an exceptional candidate to the post of Research Fellow in the Wellcome Wolfson Institute for Experimental Medicine.

The Tiwari Lab (www.tiwarilab.com) is looking for a computational postdoc. Our team works on single-cell genomics and gene regulation, combining new single-cell and spatial omics technologies with bioinformatics and machine learning. In this project the candidate will develop new computational strategies to identify human genetic variation linked to cell fate changes in the human brain, with a particular focus on brain regions affected by neurodevelopmental disorders. The candidate can use and combine single-cell ATAC-seq, single-cell RNA-seq, spatial gene expression, and whole-genome sequencing (with long reads) data. The candidate will get the opportunity to explore new analysis methods using deep learning. Depending on the interest, it is also possible to be involved in the wet-lab, to perform single-cell sequencing and other experiments.

Selected publications from Tiwari lab

Nature Cell Biology, 2022, in press; Genes & Development, 2020, Sep; 34(17-18):1190-1209; Nature, 2019, Mar; 567(7746):113-117; Cell Stem Cell, 2018, Oct 4; 23(4):557; Nature Communications, 2017 Nov 15;8(1):1523; The EMBO Journal, 2016 Jan 4;35(1):24-45; J Cell Science, 2015 Dec 1;128(23):4380-94; The EMBO Journal, 2015 Aug 13;34(16):2162-81; Genome Research, 2015 Sep;25(9):1309-24; Nature Communications, 2013, Sep 27; 4:2478; Cancer Cell, 2013, 23, 768-783; PNAS, 2012 Apr 17;109(16): E934-43; Nature Genetics, 2012 Jan; 18;44(1):94-100; Nature, 2011 Dec 14;480(7378):490-5.

The successful candidate must have and your CV/Cover letter (or application form) should clearly demonstrate you have:

• Have or about to obtain a PhD in Bioinformatics or Computational Biology or Systems Biology or related areas.

•3 years recent relevant work experience (includes PhD) to include:

- Programming skills in one of the following languages: R, Perl, Python, C/C++, SBML, Fortran or Shell scripting;

- Experience in analysing high throughput genomics datasets such as single-cell RNA-seq, ATAC-seq

•At least one recent high-quality original research publication in a reputable peer-reviewed journal, commensurate with career stage

Please note the above are not an exhaustive list.

Fixed term contract posts are available for the stated period in the first instance but in particular circumstances may be renewed or made permanent subject to availability of funding.

Key Dates

Closing Date: 15/08/2022

Anticipated Interview Date: 23/08/2022

Further Information

Informal enquiries may be directed to Dr David Simpson at David.Simpson@qub.ac.uk

Information about the School can be found at https://www.qub.ac.uk/research-centres/wwiem/

At Queen’s our people are at the heart of everything we do. As a staff member you will become part of a vibrant organisational culture, which will provide you with the opportunity to achieve your full potential and enhance your career through a continuous focus on learning and development.

We offer an excellent employment package that includes:

• Great terms & conditions

• Pension schemes

• Family-friendly initiatives

• Career development opportunities

• Support for health & mental wellbeing

• Generous holiday entitlement of 8 weeks a year (made up of 23 days annual leave, 10 closure days and 9 bank holidays)

Further information on our attractive package can be found at: https://www.qub.ac.uk/directorates/HumanResources/pay-reward-and-benefits/

Queen’s University is committed to promoting equality of opportunity to all. We have created an inclusive culture by establishing staff networks such as iRise (Race) and PRISM (LGBTQ+) which help us progress equality.

We also subscribe to Equality Charter Marks such as the Diversity Charter Mark NI in addition to Athena Swan. For further information on our commitment to Equality, Diversity and Inclusion, please visit: www.qub.ac.uk/diversity; https://www.qub.ac.uk/sites/QueensGenderInitiative/ and www.qub.ac.uk/sites/StaffGateway/StaffNetworks/

For further information about the role including the essential and desirable criteria please visit www.qub.ac.uk/jobs or click to Apply.

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