Postdoc in Immunology / Mechanisms of Allergic Disease (M/F/D)

Heidelberg University Hospital

Job description

Compromised epithelial barriers are among the key risk factors for allergic sensitization. How barrier-defective skin communicates with innate and adaptive immunity, however, to induce pathogenic type 2 and IgE responses, is only partially resolved. In the setting of a national research network (https: // www. for2599.de) we address this question using mouse models of skin barrier defects and human samples, as well as mice deficient for immune mediators or cell types. We study the impact of these alterations on the innate and adaptive immune system at high resolution relying on flow cytometry and single cell OMICS technologies and validate candidate factors by CRISPR- based mutagenesis.

A successful candidate will use

  genetic engineering (CRISPR, recombineering)

  mouse genetics, conditional gene targeting

  single cell RNA sequencing

  cell culture

  immunohistochemistry

  flow cytometry

Your profile

We are looking for a dedicated and enthusiastic PhD or MD, experienced in life science research, preferably in immunology and with the following skills:

  experience with some of the above-mentioned technology (not mandatory)

  experience in writing scientific publications

  motivation to work independently and to develop a research field

We offer

  A vibrant international research environment

  A comprehensive spectrum of key technology

  Collaborative work in a friendly team

  Flexible working hours

  Target-oriented individual further education and training opportunities

  Targeted training on the job

  Ticket for public transport

  Possibility of child care (crèche and kindergarten) as well as subsidy for holiday care for school children

  Active health promotion

  Company pension scheme

  Access to the university library and other university facilities (e.g. university sports)

Contact & Application

We are looking forward for your application by email.

Applicants should submit a full CV, list of publications and a motivation letter including a description of previous research experience, a summary of the PhD thesis, certificates and recommendation letters or contact details of referees.

For any questions please contact Professor Axel Roers by phone or mail: axel.roers@tu-dresden.de.

Universitätsklinikum Heidelberg Institut für Immunologie Prof. Axel Roers Im Neuenheimer Feld 305 69120 Heidelberg phone: +49 351 458 6500 / +49 6221 56 4037 hannelore.frank@immu.uni-heidelberg.de

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