美国贝勒医学院神经科学博士后招聘

　　Job Description

　　Summary

　　The Jankowsky lab seeks a postdoctoral fellow for an NIH-funded project to examine how genetic variants shape cognitive resilience in Alzheimer's disease.  We have created knock-in and knock-out mice to examine the function of a candidate disease modifier and are poised to take our studies in several exciting new directions.  First, we want bring transcriptional analyses to our studies for comparison of downstream changes in vulnerable vs. resistant brain areas and cell types.  Second, we want to determine how this modifier affects neuronal structure and connectivity through single cell labeling and image-based reconstruction in cleared tissue.  Ongoing work in the lab will connect these molecular and structural studies with electrophysiological and behavioral testing.  We seek a motivated candidate who is intellectually and experimentally flexible enough to tackle these new lines of study with us.  Researchers will work as part of a team combining mouse genetic engineering, viral circuit manipulation, hippocampal slice electrophysiology, and basic biochemistry to elucidate the complex interaction between genetics, aging, and cognitive health.

　　Job Purpose

　　Postdoctoral Associates are trainees working in an apprenticeship mode in preparation for a career as a scientific professional

　　Job Responsibilties

　　Plans, directs and conducts specialized and advanced research experiments.

　　Evaluates and analyzes data.

　　May establish new research protocols and procedures.

　　Summarizes research findings and publish results in research journals.

　　May be responsible for laboratory operations.

　　May supervise research staff.

　　Minimum Qualifications

　　Education: Ph.D in Neuroscience or related discipline

　　Experience: None Required

　　Skills: Strong background in molecular biology, highly self-motivated with outstanding experimental skills, able to think independently but also work well in a team.

　　Preferred Qualifications

　　Experience: Experience with transgenic/knockin/knockout mouse models, transcriptomics, or advanced fluorescence imaging.

　　Other

　　The laboratory is located at the main Baylor College of Medicine campus which enjoys a vibrant and collegial scientific environment.  BCM itself is located in Houston's Texas Medical Center, a 1,000-acre complex of over 50 independent institutions within easy access. Houston is the fourth largest city in the US and is home to a diverse international population.  The city offers great restaurants, a warm climate, and affordable housing.