招聘简介：

　　由Andrea Ablasser领导的洛桑理工学院（EPFL）先天免疫实验室邀请申请博士后职位。

　　“细胞内先天免疫”

　　DNA具有高度免疫原性。微生物DNA是宿主先天免疫系统检测到的关键病原相关分子模式。同样地，宿主dnacan也会引发有效的先天免疫反应，一方面支持抗肿瘤免疫，另一方面也会引发有害的炎症或自身免疫反应。我们的研究旨在在分子水平上描述先天性DNA传感机制的调节机制，最终目的是为炎症性疾病的治疗干预制定新的策略。

　　博士后职位的申请人应持有生物科学（生物）化学或相关学科背景的生命科学博士学位，并应在同行评审的期刊上有良好的出版记录。我们正在寻找对科学和研究充满热情、有才华、有创造力和热情的候选人。

　　我们的实验室是一个高度协作的环境，重视严格的研究。它位于瑞士两所联邦理工学院之一的EPFL主校区，日内瓦湖沿岸，阿尔卑斯山脚下。

　　英文原文：

　　The Laboratory of Innate Immunology headed by Andrea Ablasser at the École Polytechnique Fédérale de Lausanne (EPFL) invites application for a Postdoc Position on

　　“Intracellular innate immunity”

　　DNA is highly immunogenic. Microbial DNA serves as a key pathogen-associated molecular pattern detected by the host innate immune system. Likewise, host DNAcan also trigger potent innate immune response that one the one hand supports antitumor immunity, but on the other hand also fuels deleterious inflammatory or autoimmune reactions. Our research aims to describe at the molecular level the mechanisms underlying the regulation of innate DNA sensing mechanisms with the ultimate goal to define new strategies for therapeutic interventions into inflammatory diseases.

　　Applicants for the Postdoc position should hold a Ph.D. in life sciences with a background in biological sciences, (bio)chemistry or a related discipline and should have a strong publication record in peer-reviewed journals. We are looking for talented, creative and enthusiastic candidates passionate for science and research.

　　Our laboratory is a highly collaborative environment that values rigorous research. It is located at the main campus of EPFL, one of the two Swiss Federal Institutes of Technology, on the shores of Lake Geneva and at the foot of the Alps.

　　Further details can be found on our website at ablasserlab@epfl.ch. Candidates are also encouraged to consult recent publications of the laboratory:

　　Ablasser and Chen, Science 2019

　　Haag et al., Nature 2018

　　Glück et al., Nature Cell Biology 2017

　　Gulen et al., Nature communications 2017