招聘简介：
突触传递机制及其对神经回路输出的影响
爱荷华州爱荷华州卡弗医学院的塞缪尔杨实验室有一个开放的博士后职位。https://young.lab.uiowa.edu/twitter@samyounglab这个年轻的实验室关注的是一个基本问题：突触如何使神经元回路传输广泛多样的信息？我们的研究成果将定义控制突触特性如何驱动神经元回路输出的分子原理，这是有机体行为的基础。
我们使用保持/mntb突触的花萼。这个模型系统提供了无与伦比的机会来深入了解支持听觉处理初始阶段的突触前机制。该实验室采用了一种综合方法，将新的病毒载体技术、电生理和生物物理方法、生物化学、光学和电子显微镜技术与转基因小鼠结合使用。研究重点的两个主要领域是快速听觉信号的突触前释放机制和突触前Cav2通道功能。
候选人必须拥有相关科学学科的博士学位和至少一本第一作者出版物。在实验室使用的任何方法方面的专业知识优先。感兴趣的应聘者应提交简历、求职信和完整的联系信息，至少三份有关以下职位@uiowa链接的参考资料：
https://jobs.uiowa.edu/postdoc/view/3128
英文原文：
Mechanisms of Synaptic transmission and Impact on Neuronal Circuit Output
There is an open post-doctoral position in the laboratory of Samuel Young at the University of Iowa Carver College of Medicine, Iowa City, IA. https://young.lab.uiowa.edu/ Twitter @samyounglab The Young laboratory is focused on the fundamental question: How do synapses enable neuronal circuits to transmit a wide diversity of information? Outcomes from our work will define the molecular principles that govern how synaptic properties drive neuronal circuit output, which underpins organism behavior.
We use the calyx of Held/MNTB synapse. This model system which provides unparalleled opportunities to gain insights into the presynaptic mechanisms that support the initial stages of auditory processing. The laboratory uses an integrated approach that centers on using novel viral vector technology, electrophysiological and biophysical methods, biochemistry, light and electron microscopy techniques in conjunction with transgenic mice. Two major areas of research focus are presynaptic release mechanisms for fast auditory signaling and presynaptic CaV2 channel function
Candidates must have a PhD in a related scientific discipline and at least one first author publication. Expertise in any of the approaches used in the laboratory are preferred. Interested candidates should submit their Curriculum Vitae, a cover letter and complete contact information for at least three references to the Jobs@UIOWA link below:
https://jobs.uiowa.edu/postdoc/view/3128
