招聘简介：

　　博士后研究助理：分子生物学家/生物化学家探索DNA碱基修饰及其表观遗传功能（固定期限）

　　化学系

　　参考：MA17561

　　定期：该职位的资金首次提供2年。

　　我们寻求博士后科学家与Shankar Balasubramanian教授合作，参与Wellcome Trust资助的项目，研究核酸碱基修饰的表观遗传作用。这是一个跨学科项目，包括化学生物学，分子生物学和基因组学。 Seehttps：//www.balasubramanian.co.uk/了解更多信息。

　　英文原文：

　　Postdoctoral Research Associate: Molecular biologist/biochemist to exploreDNAbase modifications and their epigenetic functions (Fixed Term)

　　Department of Chemistry

　　£32,236-£39,609

　　Reference: MA17561

　　Fixed-term: The funds for this post are available for 2 years in the first instance.

　　We seek a postdoctoral scientist to work with Professor Sir Shankar Balasubramanian on a Wellcome Trust-funded programme to investigate the epigenetic role of nucleic acid base modifications. This is an interdisciplinary project that encompasses chemical biology and molecular biology and genomics. Seehttps://www.balasubramanian.co.uk/ for further information.

　　We look to appoint a molecular biologist or biochemist to carry out research on how chemically modified bases affect the structure and function of DNA. The investigations will involve a consideration of the chemistry and enzymology of modified bases, protein-DNA interactions, chromatin structure and transcription. We aim to manipulate the epigenetic states of systems as part of our studies. This will enable us to gain a deeper understanding of the function of base modifications and their involvement in regulating gene expression in normal and disease states using cellular models from human, and mouse and parasite models.

　　The successful candidate will have a capacity for innovation and creativity. Strong communication skills and the ability to work effectively as part of a multi-disciplinary team will be important. Experience in working in an interdisciplinary environment, particularly with chemists/chemical biologists would be an advantage.

　　Candidates should have (or be about to receive) a PhD in a relevant discipline.

　　The position is available immediately.

　　Previous applicants need not apply.

　　To apply online for this vacancy and to view further information about the role, please visit :

　　http://www.jobs.cam.ac.uk/job/19728/

　　Closing date: 18 April 2019

　　Please ensure that you upload a 2-page Curriculum Vitae (CV), a covering letter that explains your motivations for the position and your publications list in the Upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.

　　For queries regarding applying online for this post, please contact Jo Lockhart, PA to Professor Sir Shankar Balasubramanian, email: BalasubramanianRecruitment@ch.cam.ac.uk

　　Please quote reference MA17561 on your application and in any correspondence about this vacancy.

　　The Department holds an Athena SWAN silver award for women in science, technology, engineering, mathematics and medicine.

　　The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

　　The University has a responsibility to ensure that all employees are eligible to live and work in the UK.