Postdoctoral Position at

　　University of Pennsylvania School of Medicine

　　Children’s Hospital of Philadelphia

　　A postdoctoral position is available to

　　investigate cytokine receptor signaling in replication stress and DNA repair.

　　Dr. Tong’s laboratory studies cytokine receptor and ubiquitin signaling in hematopoietic

　　stem cells, bone marrow failure, and leukemia. Hematopoietic stem cells give

　　rise to all circulating blood cells throughout life. Maintenance of stem cell

　　self-renewal, proliferation and differentiation is regulated by complex

　　signaling pathways. Aberrant regulation leads to leukemia. Genome integrity

　　plays a critical role in the prevention of leukemia, ageing, and blood

　　development. This postdoctoral fellow position will focus on studying the

　　mechanisms that safeguard the genome during DNA replication and investigating

　　how failures in these processes impact hematopoietic stem cell function that

　　leads to bone marrow failure and/or leukemia. You can find our recent

　　publication in below website.

　　https://www.med.upenn.edu/apps/faculty/index.php/g20000220/p8146029

　　Candidates should have a Ph.D. or equivalent

　　degree and experience with investigating biochemistry, cell biology, molecular

　　biology, as well as mouse models.

　　Highly motivated candidates with publication

　　records are encouraged to apply. Please email or send applications with a brief

　　statement of research experience and interest, CV, and contact information for

　　at least two references to:

　　Wei Tong, Ph.D

　　Associate

　　Professor of Pediatrics,

　　Children’s Hospital of Philadelphia,

　　University of Pennsylvania School of Medicine,

　　Co-Director, Hematopoietic Stem Cell program,

　　Institute for Regenerative Medicine at UPENN

　　Abramson

　　Bldg. 310D,

　　3615 Civic Center Blvd.,

　　Philadelphia, PA 19104

　　Tel: 267-426-0930

　　Fax: 267-426-5476